𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Frequent mutations of the Trp53, Hras1 and β-catenin (Catnb) genes in 1,3-butadiene-induced mammary adenocarcinomas in B6C3F1 mice

✍ Scribed by Zhuang, Shi-Mei; Wiseman, Roger W; Söderkvist, Peter


Book ID
110066825
Publisher
Nature Publishing Group
Year
2002
Tongue
English
Weight
147 KB
Volume
21
Category
Article
ISSN
0950-9232

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


Increased frequency of mutations at A:T
✍ Leslie Recio; Kathy G. Meyer 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 English ⚖ 676 KB

W e have examined the spectra of mutations in a collection of 7 4 lac1 mutants isolated from the bone marrow of B6C3F1 lac1 transgenic mice exposed to 1,250 ppm 1,3-butadiene (BD). Of the 49 inde pendent mutations analyzed in the present study, 30 of 49 (61 %) were point mutations at G:C base pairs,