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Role of β-Catenin in Synaptic Vesicle Localization and Presynaptic Assembly

✍ Scribed by Shernaz X. Bamji; Kazuhiro Shimazu; Nikole Kimes; Joerg Huelsken; Walter Birchmeier; Bai Lu; Louis F. Reichardt

Book ID
117608821
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
724 KB
Volume
40
Category
Article
ISSN
0896-6273

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The tyrosine kinase pp60src is known to phosphorylate synaptophysin and in doing so may regulate neurotransmitter release. The tyrosyl phosphorylated state of synaptophysin is dependent on pp60src kinase and the unknown protein tyrosine phosphate phosphohydrolase (PTPase, EC 3.1.3.48). Here we repor