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Role of X-linked inhibitor of apoptosis protein in chemoresistance in ovarian cancer: possible involvement of the phosphoinositide-3 kinase/Akt pathway

✍ Scribed by Jin Q Cheng; Xiuxian Jiang; Michael Fraser; Ming Li; Han C Dan; Mei Sun; Benjamin K Tsang

Book ID: 117764470
Publisher: Elsevier Science
Year: 2002
Tongue: English
Weight: 446 KB
Volume: 5
Category: Article
ISSN: 1368-7646
DOI: 10.1016/s1368-7646(02)00003-1

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## Abstract The major obstacle to successful treatment of gastric cancer is chemotherapy resistance. Our study was designed to investigate the role of phosphoinositide 3‐kinase (PI3K)/Akt pathway in the development of chemoresistance in gastric cancer. In the present study, elevated Akt expression