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Role of Transferrin Receptors and Endocytosis in Iron Uptake by Hepatic and Erythroid Cells

โœ Scribed by Evan H. Morgan; Erica Baker


Book ID
119862472
Publisher
John Wiley and Sons
Year
1988
Tongue
English
Weight
933 KB
Volume
526
Category
Article
ISSN
0890-6564

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โœ Laura M. Garrick; Kevin G. Dolan; Michelle A. Romano; Michael D. Garrick ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 261 KB ๐Ÿ‘ 2 views

Belgrade (b) rats have an autosomal recessive, microcytic, hypochromic anemia. Transferrin (Tf)-dependent iron uptake is defective because of a mutation in DMT1 (Nramp2), blocking endosomal iron efflux. This experiment of nature permits the present study to address whether the mutation also affects