Role of the system for superoxide radical formation and detoxication in the mechanism of the antitumor effect of adriamycin
β Scribed by A. M. Tarakhovskii; E. N. Zhmareva; S. A. Romodanov
- Publisher
- Springer US
- Year
- 1983
- Tongue
- English
- Weight
- 171 KB
- Volume
- 96
- Category
- Article
- ISSN
- 0007-4888
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
This review summarizes recent developments on the mechanisms by which adenosine is formed in the cardiovascular system. The concept is developed that AMP is both a precursor of adenosine but also a product when rephosphorylated by adenosine kinase. The functional significance of this metabolic cycle
Formation of hydrogen peroxide, the dismutation product of superoxide radical, has been demonstrated in erythrocytes incubated with the mycotoxin sporidesmin. Erythrocytic thiols, both non-protein and protein-bound, were depleted in the presence of sporidesmin, whilst haemoglobin was oxidized to met
The mcthylviologen radical cation MV + has been generated in lhe solid sLate either from the MVC12 Salk, by heating or by laser irradiation at 6471 br. or horn the MV'+ cation intercalated in the CdPS, lamellar hosl lake. by chemical reduclion. In each case the mechanism of formarion is discussed an
Plasma membrane samples from rat brain, heart, and liver were examined for biochemical changes with age. A rise in superoxide radical (SOR) levels was followed by increases in thiobarbituric acid reactive substances and decreases in membrane fluidity with age. The earliest rise in SOR formation appe