𝔖 Bobbio Scriptorium
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Role of the MRP1/ABCC1 Multidrug Transporter Protein in Cancer

✍ Scribed by Marcia Munoz; Michelle Henderson; Michelle Haber; Murray Norris

Book ID
111741957
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
648 KB
Volume
59
Category
Article
ISSN
1521-6543

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The ATP-binding cassette (ABC) transporter ABCC1, or multidrug resistance-related protein 1 (MRP1) is implicated in Phase II metabolism and multidrug resistance as it effluxes substrate anticancer drugs. As cannabinoids inhibit two related ABC transporters, P-glycoprotein and ABCG2, here we examined