Interaction of plant cannabinoids with t
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Michelle L. Holland; John D. Allen; Jonathon C. Arnold
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Article
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2008
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Elsevier Science
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English
β 217 KB
The ATP-binding cassette (ABC) transporter ABCC1, or multidrug resistance-related protein 1 (MRP1) is implicated in Phase II metabolism and multidrug resistance as it effluxes substrate anticancer drugs. As cannabinoids inhibit two related ABC transporters, P-glycoprotein and ABCG2, here we examined