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Role of the inhibition of NF-κB activation during PGE1 protection against D-galactosamine-induced apoptosis in primary culture of rat hepatocytes

✍ Scribed by D. Fouad; J.L. Montero; M. De la Mata; J. Muntane


Book ID
118566028
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
158 KB
Volume
38
Category
Article
ISSN
0168-8278

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PGE1-induced NO reduces apoptosis by D-g
✍ Emilio Siendones; Dalia Fouad; María José M. Díaz-Guerra; Manuel de la Mata; Lis 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 235 KB

Prostaglandin E 1 (PGE 1 ) reduces cell death in experimental and clinical liver dysfunction. We have previously shown that PGE 1 preadministration protects against NO-dependent cell death induced by D-galactosamine (D-GalN) through a rapid increase of nuclear factor B (NF-B) activity, inducible NO