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Role of the histone deacetylase complex in acute promyelocytic leukaemia

โœ Scribed by Evans, Ronald M.; Lin, Richard J.; Nagy, Laszlo; Inoue, Satoshi; Shao, Wenlin; Miller, Wilson H.


Book ID
109781552
Publisher
Nature Publishing Group
Year
1998
Tongue
English
Weight
415 KB
Volume
391
Category
Article
ISSN
0028-0836

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Role of histone deacetylases in acute le
โœ Randy Fenrick; Scott W. Hiebert ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 107 KB ๐Ÿ‘ 2 views

Accumulating evidence points to a connection between cancer and transcriptional control by histone acetylation and deacetylation. This is particularly true with regard to the acute leukemias, many of which are caused by fusion proteins that have been created by chromosomal translocations. Genetic re