Requirement for myeloid growth factors in the differentiation of acute promyelocytic leukaemia
β Scribed by William Matsui; B. Douglas Smith; Milada Vala; Nikeshia Beal; Carol Ann Huff; Louis F. Diehl; Richard J. Jones
- Book ID
- 108673085
- Publisher
- John Wiley and Sons
- Year
- 2005
- Tongue
- English
- Weight
- 235 KB
- Volume
- 128
- Category
- Article
- ISSN
- 0007-1048
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Differentiation inducing agents in double and triple combinations can induce differentiation in primary culture of more than 80% of blast cells from some AML patients. In the present study, the interactions between these differentiating agents have been analysed using Berenbaum's general algebraic s
## Abstract Normal hematopoietic cells require the presence of a protein (MGI) in the appropriate conditioned medium (CM) for cell viability and growth and for differentiation to mature macrophages and granulocytes. Clones of myeloid leukemic cells have been established in culture (D^+^ clones) whi