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Role of the BRAF Mutations in the Microsatellite Instability Genetic Pathway in Sporadic Colorectal Cancer

✍ Scribed by M. L. Maestro; M. Vidaurreta; M. T. Sanz-Casla; S. Rafael; S. Veganzones; A. Martínez; C. Aguilera; M. D. Herranz; J. Cerdán; M. Arroyo


Book ID
111771760
Publisher
Springer
Year
2006
Tongue
English
Weight
209 KB
Volume
14
Category
Article
ISSN
1068-9265

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## Abstract It is generally accepted that both dysfunction of the Wnt signaling pathway, including mutations in the adenomatous polyposis coli (__APC__) and β‐catenin genes, and genetic instability play important roles in colorectal carcinogenesis. However, alteration of the components in the Wnt s