Role of the basic helix-loop-helix protein ITF2 in the hormonal regulation of Sertoli cell differentiation
β Scribed by Terla Muir; Ingrid Sadler-Riggleman; Jeffrey D. Stevens; Michael K. Skinner
- Book ID
- 111663948
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 245 KB
- Volume
- 73
- Category
- Article
- ISSN
- 1040-452X
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π SIMILAR VOLUMES
HES-1 is a vertebrate homologue of the Drosophila basic helix-loop-helix (bHLH) protein Hairy, a transcriptional repressor that negatively regulates neuronal differentiation. HES-1 expression in neuronal precursors precedes and represses the expression of the neuronal commitment gene MASH-1, a bHLH
## Abstract ## BACKGROUND. Inhibitor of DNA binding 2 (Id2), a helixβloopβhelix protein of the inhibitor of differentiation (ID) family, is involved in hematopoiesis, mainly through interaction with the Eβfamily of transcription factors. Recent studies have shown that Id2 is overexpressed in some