✦ LIBER ✦

Role of T-cell subsets in bacterial infections

✍ Scribed by Stefan H.E. Kaufmann

Publisher: Elsevier Science
Year: 1991
Tongue: English
Weight: 865 KB
Volume: 3
Category: Article
ISSN: 0952-7915
DOI: 10.1016/0952-7915(91)90004-k

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✦ Synopsis

Classic functional partitioning of T-cell subsets is being questioned: in many bacterial and protozoan infections, CD8 T cells play a role in protection; two types of CD4 T helper cells have been characterized, one protective, the other exacerbating disease; finally, gamma delta T cells have been implicated in the host response to certain bacteria. Moreover, evidence is accumulating that, in addition to T-cell helper functions, cytolytic T-cell functions participate in antibacterial immunity.

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