## Abstract The mainstay of treatment for thrombotic thrombocytopenic purpura (TTP) is plasma exchange (PE), but the role of splenectomy is still undefined. The records of all patients with TTP at a single center over a 20βyear period were retrospectively reviewed. Response to plasma exchange was d
Role of splenectomy as a salvage procedure in thrombotic thrombocytopenic purpura
β Scribed by A. D. Wells; Mr A. E. Young; G. Majumdar; N. G. P. Slater
- Publisher
- John Wiley and Sons
- Year
- 1991
- Tongue
- English
- Weight
- 223 KB
- Volume
- 78
- Category
- Article
- ISSN
- 0007-1323
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π SIMILAR VOLUMES
Plasma exchange (PE) is considered first-line treatment for thrombotic thrombocytopenic purpura (TTP) to the point that many clinicians regard it as definitive therapy. Studies have reported response rates to PE ranging from 39% to 78%. In our experience, a minority of patients have been cured solel
Some patients with thrombotic thrombocytopenic purpura (TTP) remain plasmaexchange-dependent for prolonged periods of time. This exposes patients to risk, uses substantial resources, and requires prolonged hospitalization. We have splenectomized 7 such patients following 25-42 plasma exchanges while