BACKGROUND. This study examined the impact of secondary cytoreductive surgery on survival of patients with recurrent epithelial ovarian carcinoma. ## METHODS. One hundred six patients with a disease free interval (DFI) ΟΎ 6 months after primary treatment underwent secondary cytoreductive surgery. M
Role of salvage cytoreductive surgery in the treatment of patients with recurrent ovarian cancer after platinum-based chemotherapy
β Scribed by Aya Matsumoto; Toshihiro Higuchi; Shigeo Yura; Masaki Mandai; Masatoshi Kariya; Kenji Takakura; Shingo Fujii
- Book ID
- 109006565
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 169 KB
- Volume
- 32
- Category
- Article
- ISSN
- 1341-8076
No coin nor oath required. For personal study only.
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## Background and Objectives: We assessed the role of salvage chemotherapy with topotecan and cisplatin in patients with platinum-and paclitaxel-resistant advanced and recurrent ovarian or primary peritoneal cancer, based on the reported in vivo and in vitro synergism between these two drugs. Meth
## Abstract ## Aims Recent retrospective trials stated that a benefit of surgery for recurrent ovarian cancer may be limited to patients in whom a complete cytoreduction (R0) could be achieved. Most of them pointed out there was no difference in survival between residual disease of 0.1β1βcm (R1) a