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Role of RNA synthesis in DNA replication of synchronized populations of cultured mammalian cells

โœ Scribed by Yoshisada Fujiwara

Publisher
John Wiley and Sons
Year
1967
Tongue
English
Weight
708 KB
Volume
70
Category
Article
ISSN
0021-9541

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โœฆ Synopsis

Using the harvesting method of synchronizing L cells, the relationship of RNA synthesis to DNA replication was studied by the use of selective inhibitors o, C RNA synthesis such as actinomycin D and chromomycin succinate. The synthesis of the early replicating DNA fraction is a process sensitive to the inhibition of RNA synthesis during the G1 period.

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