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Role of Rho, Rac, and Rho-kinase in phosphorylation of myosin light chain, development of polarity, and spontaneous migration of Walker 256 carcinosarcoma cells

✍ Scribed by Marc C. Gutjahr; Jérémie Rossy; Verena Niggli

Book ID
118506171
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
863 KB
Volume
308
Category
Article
ISSN
0014-4827

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Signal transduction pathways controlling tumor cell locomotion are not yet well understood. We have studied the role of protein kinase C (PKC)-dependent protein phosphorylation associated with changes in cell shape and locomotor activity of Walker carcinosarcoma cells in culture. We show that the in