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Differential roles of Rho-kinase and myosin light chain kinase in regulating shape, adhesion, and migration of HT1080 fibrosarcoma cells

โœ Scribed by Verena Niggli; Manuela Schmid; Alexandra Nievergelt

Book ID
116292576
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
253 KB
Volume
343
Category
Article
ISSN
0006-291X

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Protein kinase C isoforms involved in re
Protein kinase C isoforms involved in regulation of cell shape and locomotion of human fibrosarcoma HT1080 cells
โœ H.U. Keller; I.P. Hunziker; B. Sordat; V. Niggli; J. Sroka ๐Ÿ“‚ Article ๐Ÿ“… 2000 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 215 KB

The role of protein kinase C (PKC) isoforms in the regulation of cell shape [switch between fibroblast-like and crescent shape (CS)] and of locomotion of human fibrosarcoma HT1080 cells has been investigated. The PKC activator phorbol myristate acetate (PMA) induced the transition of elongated fibro