✦ LIBER ✦

Role of regulatory T cells in allergy and asthma

✍ Scribed by Omid Akbari; Philippe Stock; Rosemarie H DeKruyff; Dale T Umetsu

Publisher: Elsevier Science
Year: 2003
Tongue: English
Weight: 196 KB
Volume: 15
Category: Article
ISSN: 0952-7915
DOI: 10.1016/j.coi.2003.09.012

No coin nor oath required. For personal study only.

✦ Synopsis

Th2 cells play a critical role in the pathogenesis of allergy and asthma. However, the immunological mechanisms that downmodulate and protect against the development of these disorders are poorly understood. A spectrum of CD4 þ T cells, including Th3 cells, T R cells, CD4 þ CD25 þ cells and NKT cells play a critical role in regulating these diseases. A better understanding of the role of regulatory cells in allergic diseases may lead to the identification of novel therapeutic targets.

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