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Role of protein kinases, protein phosphatases and extracellular signals in the abnormal hyperphosphorylation of tau

โœ Scribed by Inge Grundke-Iqbal; Yoshitaka Tatebayashi; Cheng-Xin Gong; Jun Zhong; Niloufar Haque; Khalid Iqbal


Book ID
117412110
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
186 KB
Volume
21
Category
Article
ISSN
0197-4580

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Canine cardiac sarcoplasmic reticulum is phosphorylated by adenosine 3',5'-monophosphate (cAMP)-dependent and by calcium.calmodulin-dependent protein kinases on a 27,000 proteolipid, called phospholamban. Both types of phosphorylation are associated with an increase in the initial rates of Ca2+ tran