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Role of protein kinase C in growth stimulation of primary mouse colonic epithelial cells

✍ Scribed by Christina Branting; Rune Toftgård; Inger Porsch Hällström; Joseph Rafter

Book ID
112803501
Publisher
Society for In Vitro Biology
Year
1995
Tongue
English
Weight
874 KB
Volume
31
Category
Article
ISSN
1475-2689

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✍ Gadiraju Ramesh; Alan E. Levine 📂 Article 📅 1995 🏛 John Wiley and Sons 🌐 French ⚖ 842 KB

The human colon cancer cell lines HCT I I 6 (poorly differentiated) and GEO (well differentiated) express the mitogenic peptide transforming growth factor alpha (TGF-a). The secretion of TGF-awas enhanced by phorbol 12-myristate 13-acetate (PMA), indicating the possible role of protein kinase C (PKC