✦ LIBER ✦

Role of plasma membrane and of cytomatrix in maintenance of intracellular to extracellular ion gradients in chicken erythrocytes

✍ Scribed by I. L. Cameron; K. E. Hunter; N. K. R. Smith; C. F. Hazlewood; A. Ludany; M. Kellermayer

Publisher: John Wiley and Sons
Year: 1988
Tongue: English
Weight: 607 KB
Volume: 137
Category: Article
ISSN: 0021-9541
DOI: 10.1002/jcp.1041370213

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✦ Synopsis

Ultrastructural observations in combination with electron probe X-ray microanalysis on detergent (Brij 58) permeabilized (disruption of the plasma membrane) nucleated chicken erythrocytes support the view that a large fraction of cytoplasmic and nuclear K+ is not freely diffusible and that adsorption of K+ on detergent released mobilizable proteins exists within the cell. The data also suggest that the detergent proteins are normally immobilized by a detergent-resistant cytoskeleton so that they are not immediately free to diffuse from the cell for several minutes after detergent disruption of the plasma membrane.

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