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Role of peroxisomes in the biosynthesis and secretion of β-lactams and other secondary metabolites

✍ Scribed by Juan-Francisco Martín; Ricardo V. Ullán; Carlos García-Estrada

Publisher: Springer-Verlag
Year: 2011
Tongue: English
Weight: 840 KB
Volume: 39
Category: Article
ISSN: 1476-5535
DOI: 10.1007/s10295-011-1063-z

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## Abstract Pure pencillin N α‐sulfoxide (**1**) and penicillin N β‐sulfoxide (**2**) were obtained by HPLC and tested as substrates for deacetoxycephalosporin C synthetase (DXCS). Neither one of the sulfoxides was utilized under conditions of conversion of penicillin N (**8**) to deacetoxycephalos