๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Role of P-glycoprotein and cytochrome P450 3A in limiting oral absorption of peptides and peptidomimetics

โœ Scribed by Vincent J. Wacher; Jeffrey A. Silverman; Yuanchao Zhang; Leslie Z. Benet


Book ID
109389066
Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
112 KB
Volume
87
Category
Article
ISSN
0022-3549

No coin nor oath required. For personal study only.


๐Ÿ“œ SIMILAR VOLUMES


Investigation of the coordinated functio
โœ Christine D.H. Tran; Peter Timmins; Barbara R. Conway; William J. Irwin ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 233 KB

The coordination of the functional activities of intestinal CYP3A4 and P-gp in limiting the absorption of xenobiotics in Caco-2 cells was investigated. Growing Caco-2 cells were exposed to increasing concentrations of doxorubicin (1ยฑ2 mM) in plastic ยฏasks to encourage a subpopulation of cells, that