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Role of oxidized low density lipoproteins and free fatty acids in the pathogenesis of glomerulopathy and tubulointerstitial lesions in type 2 diabetes

✍ Scribed by R. Nosadini; G. Tonolo


Book ID
116800625
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
836 KB
Volume
21
Category
Article
ISSN
0939-4753

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Over 30 years after the original description of Randle's cycle, the mechanisms by which elevated circulating non-esterified fatty acids might be causally related to glucose intolerance in Type 2 diabetes mellitus remain uncertain. This review examines the evidence that elevated plasma NEFA can inhib