Role of Osteopontin in Systemic Lupus Erythematosus
โ Scribed by Kaleta, Beata
- Book ID
- 125337987
- Publisher
- Springer
- Year
- 2014
- Tongue
- English
- Weight
- 236 KB
- Volume
- 62
- Category
- Article
- ISSN
- 0004-069X
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๐ SIMILAR VOLUMES
Osteopontin (SPP1) is a soluble ligand with pleomorphic immunologic activities including activation of macrophage chemotaxis, promotion of Th1 responses, and activation of B1 B cells. It has been implicated in the development of murine lupus and is overexpressed in humans with systemic lupus erythem
Systemic lupus erythematosus (S.L.E.), commonly called lupus, is a chronic autoimmune disorder that can affect virtually any organ of the body. In lupus, the body's immune system, which normally functions to protect against foreign invaders, becomes hyperactive, forming antibodies that attack normal