An osteopontin (SPP1) polymorphism is as
โ
A.C. Forton; M.A. Petri; D. Goldman; K.E. Sullivan
๐
Article
๐
2002
๐
John Wiley and Sons
๐
English
โ 125 KB
Osteopontin (SPP1) is a soluble ligand with pleomorphic immunologic activities including activation of macrophage chemotaxis, promotion of Th1 responses, and activation of B1 B cells. It has been implicated in the development of murine lupus and is overexpressed in humans with systemic lupus erythem