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Role of Notch expression in premature senescence of murine bone marrow stromal cells

✍ Scribed by Kejie Zhang; Lifang Huang; Hanying Sun; Yan Zhu; Yi Xiao; Mei Huang; Wenli Liu

Book ID
113855903
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
332 KB
Volume
19
Category
Article
ISSN
1002-0071

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## Abstract Bone marrow stromal cells (BMSCs) can proliferate in vitro and can be transplanted for treating many kinds of diseases. However, BMSCs become senescent with long‐term culture, which inhibits their application. To understand the mechanism underlying the senescence, we investigated the ac