Role of MSH6 and PMS2 in the DNA Mismatch Repair Process and Carcinogenesis
β Scribed by Jenkins, Mark A.
- Book ID
- 122578321
- Publisher
- Elsevier Science
- Year
- 2009
- Tongue
- English
- Weight
- 109 KB
- Volume
- 18
- Category
- Article
- ISSN
- 1055-3207
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## Communicated by David Cooper Mutations of the PMS2 DNA repair gene predispose to a characteristic range of malignancies, with either childhood onset (when both alleles are mutated) or a partially penetrant adult onset (if heterozygous). These mutations have been difficult to detect, due to inte