𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Role of Mitochondria in the Mechanisms of Glutamate Toxicity

✍ Scribed by N. K. Isaev; N. A. Andreeva; E. V. Stel’mashuk; D. B. Zorov

Publisher
Springer
Year
2005
Tongue
English
Weight
407 KB
Volume
70
Category
Article
ISSN
0006-2979

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Bioenergetics of mitochondria in culture
Bioenergetics of mitochondria in cultured neurons and their role in glutamate excitotoxicity
✍ David G. Nicholls; Linda Johnson-Cadwell; Sabino Vesce; Mika Jekabsons; Nagendra 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 226 KB

## Abstract The pathologic activation of NMDA receptors by glutamate is a major contributor to neuronal cell death after stroke. Receptor activation causes a massive influx of calcium into the neuron that is accumulated by the mitochondria. The favored hypothesis is that the calcium loaded mitochon

Ionic mechanisms in glutamate-induced as
Ionic mechanisms in glutamate-induced astrocyte swelling: Role of K+ influx
✍ Alex S. Bender; Arne Schousboe; Winfried Reichelt; Michael D. Norenberg 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 434 KB 👁 1 views

L-Glutamate (L-GLU) induced astrocyte swelling in a time-and concentration-dependent, as well as Na ؉and Ca 2؉ -dependent, and Cl --independent manner. Swelling was prevented by MK-801, cystine, and ouabain. Since L-GLU swelling is ionically dependent, we determined the role of various ions in such