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Role of microglia and toll-like receptor 4 in the pathophysiology of delirium

✍ Scribed by Jalleh, Ryan; Koh, Keith; Choi, Boyoun; Liu, Ebony; Maddison, John; Hutchinson, Mark R.

Book ID
119324907
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
297 KB
Volume
79
Category
Article
ISSN
0306-9877

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## Abstract Microglia are activated by lipopolysaccharide (LPS) to produce neurotoxic pro‐inflammatory factors and reactive oxygen species (ROS). While a multitude of LPS receptors and corresponding pathways have been identified, the detailed mechanisms mediating the microglial response to LPS are