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Role of MHC class I and CD8+ T cells in the pathogenesis of chronic rejection

✍ Scribed by H Sun; V Subbotin; J Woodward; L Valdivia; J.J Fung; A.S Rao


Book ID
117230082
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
65 KB
Volume
33
Category
Article
ISSN
0041-1345

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Negative selection of Tcra-V8+CD8+T cell
✍ Kyuhei Tomonari πŸ“‚ Article πŸ“… 1992 πŸ› Springer-Verlag 🌐 English βš– 349 KB

Tcrb-V-specific positive and negative selection of T cells has been well documented. In contrast, nothing is known about Tcra-V-specific selection. Using Tcra-V8-specific KT50 antibody Tcra-V8-specific selection of T cells has been examined. The CD8+ T cell subpopulation bearing Tcra-V8 are shown to