𝔖 Bobbio Scriptorium
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Role of melatonin in Alzheimer-like neurodegeneration

✍ Scribed by Jian-zhi WANG; Ze-fen WANG


Book ID
111354987
Publisher
Nature Publishing Group
Year
2006
Tongue
Chinese
Weight
314 KB
Volume
27
Category
Article
ISSN
1671-4083

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## Abstract Accumulating evidence has indicated that gain‐of‐function in β‐amyloid production may be not the necessary mechanism for mutant presenilin‐1 (PS1) or PS2 to cause familial Alzheimer's disease (AD). In the present article, we show that conditional knockout of PS1 from the adult stage in