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Role of leukotrienes in N-(3,5-dichlorophenyl)succinimide (NDPS) and NDPS metabolite nephrotoxicity in male Fischer 344 rats

โœ Scribed by Gary O. Rankin; Suk K. Hong; Dianne K. Anestis; John G. Ball; Monica A. Valentovic; Vincent A. Graffeo

Book ID
113934183
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
953 KB
Volume
300
Category
Article
ISSN
0300-483X

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Urinary enzyme excretion as a parameter
Urinary enzyme excretion as a parameter for detection of acute renal damage mediated by N-(3,5-dichlorophenyl)succinimide (NDPS) in fischer 344 rats
โœ Monica Valentovic; Pamela Williams; John Carl Iii; Gary O. Rankin ๐Ÿ“‚ Article ๐Ÿ“… 1994 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 452 KB

The kidney has been identified as the specific target organ for in vivo exposure to an agricultural fungicide, K(3,5-dichlorophenyl)succinimide (NDPS). The goal of this study was to determine if urinary protein and enzyme excretion were sensitive, non-invasive markers for NDPS-induced renal damage.