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Effect of autacoid modulation on N-(3,5-dichlorophenyl)succinimide (NDPS) and NDPS metabolite nephrotoxicity

โœ Scribed by Gary O. Rankin; Monica A. Valentovic; Vonda J. Teets; Derek W. Nicoll; Dianne K. Anestis; Patrick I. Brown

Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
780 KB
Volume
70
Category
Article
ISSN
0300-483X

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Urinary enzyme excretion as a parameter
Urinary enzyme excretion as a parameter for detection of acute renal damage mediated by N-(3,5-dichlorophenyl)succinimide (NDPS) in fischer 344 rats
โœ Monica Valentovic; Pamela Williams; John Carl Iii; Gary O. Rankin ๐Ÿ“‚ Article ๐Ÿ“… 1994 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 452 KB

The kidney has been identified as the specific target organ for in vivo exposure to an agricultural fungicide, K(3,5-dichlorophenyl)succinimide (NDPS). The goal of this study was to determine if urinary protein and enzyme excretion were sensitive, non-invasive markers for NDPS-induced renal damage.