JNK: A double-edged sword in tumorigenes
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Francisco Javier Cubero; Gang Zhao; Christian Trautwein
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Article
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2011
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John Wiley and Sons
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English
β 309 KB
The c-Jun NH2-terminal kinase (JNK) signal-transduction pathway has been implicated in the growth of carcinogeninduced hepatocellular carcinoma. However, the mechanism that accounts for JNK-regulated tumor growth is unclear. Here, we demonstrate that compound deficiency of the two ubiquitously expre