𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Role of insulin-like growth factor-1 (IGF-1) pathway in the pathogenesis of Graves’ orbitopathy

✍ Scribed by Terry J. Smith; Laszlo Hegedüs; Raymond S. Douglas

Book ID
116305115
Publisher
Elsevier Science
Year
2012
Tongue
English
Weight
433 KB
Volume
26
Category
Article
ISSN
1521-690X

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Role of PI3K/Akt signaling in insulin-li
Role of PI3K/Akt signaling in insulin-like growth factor-1 (IGF-1) skin tumor promotion
✍ Erik Wilker; Jerry Lu; Okkyung Rho; Steve Carbajal; Linda Beltrán; John DiGiovan 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 184 KB

## Abstract Overexpression of human IGF‐1 with the bovine keratin 5 (BK5) promoter (BK5.IGF‐1 transgenic mice) induces persistent epidermal hyperplasia and leads to spontaneous skin tumor formation. In previous work, PI3K and Akt activities were found to be elevated in the epidermis of BK5.IGF‐1 tr

Skeletal unloading–induced insulin-like
Skeletal unloading–induced insulin-like growth factor 1 (IGF-1) Nonresponsiveness is not shared by platelet-derived growth factor: The selective role of integrins in IGF-1 signaling
✍ Roger K Long; Shigeki Nishida; Takuo Kubota; Yongmei Wang; Takeshi Sakata; Hashe 📂 Article 📅 2011 🏛 American Society for Bone and Mineral Research 🌐 English ⚖ 503 KB

## Abstract Integrin receptors bind extracellular matrix proteins, and this link between the cell membrane and the surrounding matrix may translate skeletal loading to biologic activity in osteoprogenitor cells. The interaction between integrin and growth factor receptors allows for mechanically in