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Role of inhibitory G protein α-subunits in adenylyl cyclase desensitization

✍ Scribed by Reithmann, C.; Gierschik, P.; Werdan, K.; Jakobs, K.H.

Book ID
123218014
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
717 KB
Volume
82
Category
Article
ISSN
0303-7207

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Heterotrimeric G-proteins, composed of alpha and betagamma subunits, transmit signals from cell-surface receptors to cellular effectors and ion channels. Cellular responses to receptor agonists depend on not only the type and amount of G-protein subunits expressed but also the ratio of alpha and bet