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G protein β1γ2subunits purification and their interaction with adenylyl cyclase

✍ Scribed by Julian Chen; Hanxiang Ni; Jingrui Sun; Gezhi Weng

Book ID
111784264
Publisher
Science in China Press (SCP)
Year
2003
Tongue
English
Weight
982 KB
Volume
46
Category
Article
ISSN
1674-7305

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## Abstract We previously demonstrated that chronic morphine induces a change in G protein coupling by the mu opioid receptor (MOR) from Gi/o to Gs, concurrent with the instatement of an interaction between Gβγ and adenylyl cyclase types II and IV. These two signaling changes confer excitatory effe