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Role of hyperforin in the antidepressant-like activity of Hypericum perforatum extract

โœ Scribed by L. Cervo; M. Rozio; C.B.Ekalle Soppo; A. Riva; P. Morazzoni; S. Caccia


Book ID
119575942
Publisher
Elsevier Science
Year
2002
Tongue
English
Weight
127 KB
Volume
12
Category
Article
ISSN
0924-977X

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The sedative activity of a hydroalcohol extract of Hypericum perforatum L. (Hypericaceae) and some of its isolated constituents was evaluated in mice. A dry hydroalcohol extract, orally administered at 26.5 mg/kg, induced a marked sedation as measured by two different tests (actimeter and sleep pote