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Role of histidine 64 in the catalytic mechanism of human carbonic anhydrase II studied with a site-specific mutant

โœ Scribed by Tu, Chingkuang; Silverman, David N.; Forsman, Cecilia; Jonsson, Bengt Harald; Lindskog, Sven


Book ID
125994572
Publisher
American Chemical Society
Year
1989
Tongue
English
Weight
725 KB
Volume
28
Category
Article
ISSN
0006-2960

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Crystallographic studies of inhibitor bi
โœ A. Elisabeth Eriksson; Per M. Kylsten; T. Alwyn Jones; Anders Liljas ๐Ÿ“‚ Article ๐Ÿ“… 1988 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 961 KB

The binding of four inhibitors--mercuric ion, 3-acetoxymercuri-4-aminobenzenesulfonamide (AMS), acetazolamide (Diamox), and thiocyanate ion--to human carbonic anhydrase II (HCA II) has been studied with X-ray crystallography. The binding of mercury to HCA II at pH 7.0 has been investigated at 3.1 A