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Kinetic and crystallographic studies of the role of tyrosine 7 in the active site of human carbonic anhydrase II

โœ Scribed by Rose Mikulski; Balendu Sankara Avvaru; Chingkuang Tu; Nicolette Case; Robert McKenna; David N. Silverman


Book ID
116178783
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
686 KB
Volume
506
Category
Article
ISSN
0003-9861

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## Abstract The role of some amino acids and metal ions in the catalytic activity of carbonic anhydrase (carbonate dehydratase EC 4.2.1.1) has been investigated. The additional stabilization of the transition state complex was used as the qualitative measure of the effect of molecular surrounding o