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Role of genetic variants in the CHRNA5–CHRNA3–CHRNB4 cluster in nicotine dependence risk: importance of gene–environment interplay

✍ Scribed by Greenbaum, L; Rigbi, A; Teltsh, O; Lerer, B

Book ID
109890007
Publisher
Nature Publishing Group
Year
2009
Tongue
English
Weight
76 KB
Volume
14
Category
Article
ISSN
1359-4184

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## Abstract Recent studies strongly support an association of the nicotinic acetylcholine receptor gene cluster __CHRNA5__–__CHRNA3__–__CHRNB4__ with nicotine dependence (ND). However, the precise genotype–phenotype relationship is still unknown. Clinical and epidemiological data on smoking behavio