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Association and interaction analysis of variants in CHRNA5/CHRNA3/CHRNB4 gene cluster with nicotine dependence in African and European Americans

✍ Scribed by Ming D. Li; Qing Xu; Xiang-Yang Lou; Thomas J. Payne; Tianhua Niu; Jennie Z. Ma


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
348 KB
Volume
9999B
Category
Article
ISSN
1552-4841

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## Abstract Recent studies strongly support an association of the nicotinic acetylcholine receptor gene cluster __CHRNA5__–__CHRNA3__–__CHRNB4__ with nicotine dependence (ND). However, the precise genotype–phenotype relationship is still unknown. Clinical and epidemiological data on smoking behavio