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Role of GATA Motifs in Tissue Factor Pathway Inhibitor Gene Expression in Malignant Cells

✍ Scribed by Madhu S. Bajaj; Darren R. Tyson; Sarah A. Steer; Mohan N. Kuppuswamy

Book ID
117256935
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
269 KB
Volume
101
Category
Article
ISSN
0049-3848

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## Abstract To identify tumor‐suppressor genes inactivated by aberrant methylation of promoter CpG islands (CGIs) in human malignant melanomas, genes upregulated by treatment of cells with a demethylating agent, 5‐aza‐2′‐deoxycytidine (5‐aza‐dC), were searched for using oligonucleotide microarrays