Role of GAP junctions in signal propagation in the nerve-hepatocyte junction
โ Scribed by Shimazu, Takashi; Iwai, Masaru
- Book ID
- 121909125
- Publisher
- Elsevier Science
- Year
- 1991
- Weight
- 97 KB
- Volume
- 16
- Category
- Article
- ISSN
- 0921-8696
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Distribution and Formation. Gap junctional channels are composed of two connexons of adjacent cells, which in turn are built up by six connexin proteins. At present, more than 20 connexin species have been cloned from humans and rodents. They all share a similar structure of four membrane-spanning d
Gap junctions between glial cells or neurons are ubiquitously expressed in the mammalian brain and play a role in brain development including cell differentiation, cell migration and survival, and tissue homeostasis, as well as in human diseases including hearing loss, neuropathies, epilepsy, brain