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Role of ethanol-inducible cytochrome P450 (P450IIE1) in catalysing the free radical activation of aliphatic alcohols

✍ Scribed by Emanuele Albano; Aldo Tomasi; Jan-Olov Persson; Ylva Terelius; Lucia Goria-Gatti; Magnus Ingelman-Sundberg; Mario U. Dianzani

Book ID
115782053
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
984 KB
Volume
41
Category
Article
ISSN
0006-2952

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πŸ“œ SIMILAR VOLUMES

Multiple mechanisms in the regulation of
Multiple mechanisms in the regulation of ethanol-inducible cytochrome P450IIE1
✍ Dennis R. Koop; Daniel J. Tierney πŸ“‚ Article πŸ“… 1990 πŸ› John Wiley and Sons 🌐 English βš– 881 KB

## Abstract Cytochrome P450IIE1 is involved in the metabolic activation of many xenobiotics involved with human toxicity. In particular, cellular concentrations of P450IIE1 are significantly induced by the most widely abused drug in our society today, alcohol. As a result, the synthesis and degrada