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Mechanisms of alcohol free radical activation by cytochrome P-450IIE1

โœ Scribed by Emanuele Albano; Aldo Tomasi; Magnus Ingelman-Sundberg


Book ID
113385371
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
132 KB
Volume
9
Category
Article
ISSN
0891-5849

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## Abstract Cytochrome P450IIE1 is involved in the metabolic activation of many xenobiotics involved with human toxicity. In particular, cellular concentrations of P450IIE1 are significantly induced by the most widely abused drug in our society today, alcohol. As a result, the synthesis and degrada