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Role of endothelin ETA receptors in sepsis-induced mortality, vascular leakage, and tissue injury in rats

✍ Scribed by Mariangela Albertini; Maria Giovanna Clement; Sabah N.A. Hussain


Book ID
114015818
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
247 KB
Volume
474
Category
Article
ISSN
0014-2999

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Modification of blood flow by endothelin-1 (ET-1) was examined in the s.c. HSN fibrosarcoma and compared to normal tissues of anaesthetised CBH/CBi rats. The ET receptor subtypes involved in the response were investigated using the ETA and ETB receptor antagonists BQ-610 and BQ-788, respectively. Bl