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Role of ETA and ETB endothelin receptors on endothelin-1-induced potentiation of nociceptive and thermal hyperalgesic responses evoked by capsaicin in rats

✍ Scribed by Emerson Marcelo Motta; Juliana Geremias Chichorro; Giles Alexander Rae


Book ID
116771287
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
471 KB
Volume
457
Category
Article
ISSN
0304-3940

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Modification of blood flow by endothelin-1 (ET-1) was examined in the s.c. HSN fibrosarcoma and compared to normal tissues of anaesthetised CBH/CBi rats. The ET receptor subtypes involved in the response were investigated using the ETA and ETB receptor antagonists BQ-610 and BQ-788, respectively. Bl